Aging & Gerontology

Biography

Daniela Frasca is Associate Professor at the University of Miami Miller School of Medicine. She has completed her graduate studies at the University of Rome “La Sapienza”. She has long-term experience on the characterization of the age-related defects in T and B lymphocytes in both mice and humans. In the last few years, as a natural extension of her previous discoveries, she has characterized the mechanisms by which obesity induces defects in B cells similar to those induced by aging, showing that obesity-associated serum inflammation induces intrinsic B cell inflammation and chronic immune activation, both leading to functional impairment of B cells and antibody responses in obese individuals. More recently, she has discovered and published that SARS-CoV-2 IgG antibodies are negatively associated with Body Mass Index as expected based on the known effects of obesity on humoral immunity. She has published 150 papers in peer-reviewed journals. She is currently serving as Associate Editor of Experimental Gerontology, Immunity & Ageing and Gerontology.