Aging & Gerontology

Can a positive outlook on aging lead to better cognitive performance

People with more positive aging expectations rate their cognitive function better and report less perceived cognitive decline, according to a new studyReadmore

Gene therapy Improves Eye Health and Reduces the Need for Anti-VEGF Injections in Age-Related Macular Degeneration.

The ABBV-RGX-314 therapy is based on a an AAV8 viral vector as a delivery system. The AAV8 platform has been genetically engineered to encode an antibody that can inhibit VEGF for the long-term.Readmore

Helaina Raises $45 Million in Series B Funding to Accelerate the Commercialization of Human Bioactive Proteins Starting with effer Human Lactoferrin

Readmore

Isolated older people more likely to have low levels of key nutrients in their diet

The researchers found that people who were more socially isolated were more likely to have a lower than recommended intake of five micronutrients that are essential for health: magnesium, potassium, vitamin C, folate and vitamin B6.Readmore

Alzheimer’s drug may slow down cognitive decline in dementia with Lewy bodies

Lewy body disease, which includes dementia with Lewy bodies (DLB) and Parkinson’s disease with and without dementia, is the second most common neurodegenerative disorder, following Alzheimer’s disease. Readmore

Gauging Biological Age and Disease Risk with a Proteomic Clock

Experimental blood test estimates age-related disease risk in diverse populations.Readmore

Nutritious diet in midlife linked to healthier aging

July 11, 2024 Eating a diet rich in fruits, vegetables, whole grains, and unsaturated fats throughout midlife may increase an individual’s odds of aging healthfully, according to a new study by researchers at Harvard T.H. Chan School of Public Health.Readmore

In Utero Undernutrition Contributes to Accelerated Biological Aging

The effects of famine were consistently larger for women and near zero for menReadmore

Chronic pain support from spouse may decrease well-being for some people

In new research by Martire and others in the Penn State College of Health and Human Development, the authors found that people who did not feel good about the pain-management support they received from a spouse or long-term romantic partner experienced moReadmore

A Fasting-Refeeding Paradigm Rejuvenates Old Stem Cells

The new study indicates that there is a way to turn back the clock to a younger time and rejuvenate these blood stem cells, restoring their ability to regenerate and fight off age-related diseases.Readmore

Olive oil may reduce risk of death from dementia

People who incorporate olive oil into their everyday diet may decrease their risk of dementia-related death, according to a new study by Harvard T.H. Chan School of Public Health.Readmore

Healthy Diet Is Linked With a Slower Pace of Aging, Reduced Dementia Risk

According to a new study by researchers at Columbia University Mailman School of Public Health and The Robert Butler Columbia Aging Center. The new study, which offers insights into the biological mechanism behind this association, appears in the Annals oReadmore

Schizophrenia and Aging May Share a Biological Basis

Synchronized changes in gene activity in brain cells may underlie cognitive impairment in both conditionsReadmore

Multi-year CIHR grant supports McMaster study at the intersection of aging and infectious disease

McMaster University researchers have received $750,000 from the Canadian Institutes of Health Research (CIHR) for a multi-year study into the connection between respiratory infections and brain aging.Readmore

Could a Drug Prevent Hearing Loss from Loud Music and Aging?

Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss.Readmore

Life span increases in mice when specific brain cells are activated

Brain cells communicate with fat tissue to produce cellular fuel, counteract effects of agingReadmore

Brock-led research uncovers breakthrough in age-related diseases

Cysteine, an essential amino acid in proteins, plays a critical role in sensing oxidative stress and signalling cells to detoxify ROS in the body. However, when cysteine undergoes trioxidation, it not only loses its detoxification function but also acquirReadmore

Researchers counter healthy aging issues, isolation in cities with $6.8 million funding

Researchers from SFU and UBC are working to counter “epidemic levels” of physical inactivity, loneliness and social isolation among older people in our cities. New funding totalling $6.8 million will help drive their efforts to promote and improve heaReadmore

Penn Medicine Receives $5 Million Grant to Study Next Generation of Dementia Treatments

Penn physicians and scientists will lead studies on underlying mechanisms of Alzheimer’s disease and related dementias with a grant from the Delaware Community FoundationReadmore

Surgery-free brain stimulation could provide new treatment for dementia

A new form of deep brain stimulation offers hope for an alternative treatment option for dementia, without the need for surgery.Readmore

Type 2 diabetes diagnosis at age 30 can reduce life expectancy by up to 14 years

An individual diagnosed with type 2 diabetes at age 30 years could see their life expectancy fall by as much as 14 years, an international team of researchers has warned.Readmore

AI-driven techniques reveal new targets for drug discovery

Researchers have developed a method to identify new targets for human disease, including neurodegenerative conditions such as Alzheimer’s disease.Readmore

Researchers find success with stem cell therapy in mice model of Alzheimers disease

In a Stanford Medicine study, scientists transplanted stem cells into mice and found reduction of brain abnormalities typical of Alzheimer’s disease.Readmore

Global ageing research consortium tackles the challenge of healthy ageing

The global partnership led by Imperial will explore how humans age and aims to develop new interventions to support healthy ageing.Readmore

Stanford Medicine-led study finds genetic factor fends off Alzheimers and Parkinsons

A massive study of medical and genetic data shows that people with a particular version of a gene involved in immune response had a lower risk of Alzheimers and Parkinson disease.Readmore

Stanford Medicine-led research identifies gene fingerprint for brain aging

A study in mice finds that white matter the tissue that transmits messages around the brain” shows the greatest changes as the animals age. Readmore

UCLA researchers lead groundbreaking studies on mammalian aging and life span

“We've discovered that the life spans of mammals are closely associated with chemical modifications of the DNA molecule, specifically known as epigenetics, or more accurately, methylation. In essence, mammals with longer life spans exhibit more pronouncReadmore

Decade-long research project that explores aging in South Africa receives NIH/NIA funding for additional waves and national expansion, with a special emphasis on cognitive health

Researchers from the Harvard Center for Population and Development Studies (HCPDS), the Harvard T.H. Chan School of Public Health, the University of the Witwatersrand, and the University of Cape Town have been awarded $27 million from the National InstituReadmore

A new molecule effectively eliminates 'zombie' cells

After sometime, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues ageingReadmore

The spectacular progress in research into slowing down aging, analyzed in Cell by Maria A. Blasco and other leading researchers in the field

• The authors have identified 12 hallmarks of aging, which are measurable processes that can be manipulated to accelerate or slow the deterioration of the body associated with aging.Readmore

Insilico Medicine reports positive Phase IIa results for ISM001-055 for the treatment of idiopathic pulmonary fibrosis (IPF) designed using generative AI

Readmore

Hypertension drug could be repurposed to delay ageing, study finds

Researchers have found that the drug rilmenidine can extend lifespan and slow ageing.Readmore

Unexpected “Scientists Discover an Anti-Aging Mechanism

The mechanism extends the life of the immune system.Readmore