Aging & Gerontology

Study finds early measure of overall health may predict future memory problems in older adults

New research shows that lower intrinsic capacity a WHO measure of overall physical and mental abilities can predict a higher risk of cognitive decline in older adults years before symptoms appear.Readmore

UCalgary research shows important links between sex hormones and brain health

Older women may face a higher risk of dementia and stroke because their brain blood vessels age faster after menopause, likely linked to rising blood pressure and declining sex hormone levels.Readmore

University of Minnesota Professor Dr. Christina Camell Earns 2025 Glenn Foundation Discovery Award

New research will investigate how signals from the immune system contribute to the loss of cellular function in aging organs.Readmore

UT Health San Antonio research shows Alzheimer’s prevention potential in pairing cannabis ingredient, anti-inflammatory drug

Recent studies show that while THC offers anti-inflammatory and neuroprotective benefits, its negative effects on learning and memory limit its clinical use in brain disorders.Readmore

A rich social environment is associated with better cognitA rich social environment is associated with better cognitive health outcomes for older adults, study findsive health outcomes for older adults, study finds

With awareness growing that lack of social connection may be a health hazard, researchers say it’s important for the public to better understand the connectionsReadmore

Menopause linked to loss of grey matter in the brain, poorer mental health and sleep disturbance

Menopause is linked to reductions in grey matter volume in key brain regions as well as increased levels of anxiety and depression and difficulties with sleep, according to new research from the University of Cambridge.Readmore

Your skin buckles as you age – and that’s why wrinkles form

Wrinkles form as aging skin stretches, contracts, and buckles due to changes in its mechanical properties over time.Readmore

New potential for treating ageing and metabolic disorders

UQ researchers found a microRNA that reduces mitochondrial stress, offering new paths for treating ageing and metabolic diseases.Readmore

Strategic gaps in ‘healthy ageing’: an analysis of global priorities

A new study reveals key biases in how stakeholders prioritize healthy ageing worldwide.Readmore

Scientists Discover a Hidden RNA “Aging Clock” in Human Sperm

New research shows that as men age, sperm RNA undergoes conserved, mid-life shifts that alter metabolism-related gene activity, offering a potential molecular explanation for increased health risks in children of older fathers.Readmore

NUS Medicine researchers identify key protein that could reverse ageing

Researchers at NUS Medicine identified DMTF1 as a key transcription factor that restores neural stem cell regeneration and may help counter age-related cognitive decline.Readmore

Exploring the role of muscles in the aging process

What determines healthspan, the term used to describe the number of years people live in good health and free from chronic disease? Muscle physiology plays a key role.Readmore

Anorexia Nervosa May Result in Long-Term Skeletal Muscle Impairment

Even after weight recovery, anorexia nervosa can cause lasting muscle loss and weakened muscle-building capacity, suggesting weight gain alone doesn’t fully restore physical health.Readmore

UNM Researchers Discover New Master Regulator of Tau, a Protein Implicated in Many Neurodegenerative Diseases

Researchers at the University of New Mexico discovered that the enzyme OTULIN promotes tau formation, brain inflammation, and aging.Readmore

To help prevent chronic health issues, UMaine researchers strengthening mental wellbeing among Downeast seniors

A University of Maine led initiative is reducing isolation and stress among older adults in rural Washington County by connecting seniors with community-based health and social support resources.Readmore

Researchers Raise Concerns about Faster Aging, Possible Early-Onset Dementia, for Children and Young Adult Cancer Survivors

A new Nature Communications study shows adolescent and young adult cancer survivors experience accelerated biological and brain aging affecting memory and attention though healthy lifestyle changes may help reverse these effects.Readmore

Study offers insight into causes of age-related inflammation

New research has identified a pathway that is triggered with age and controls both nucleolar size and the secretion of a plethora of chemicals.Readmore

Number of People with Alzheimer’s Disease May Triple by 2050

A Rush University study projects Alzheimer’s cases will triple by 2050, reaching 13.8 million due to population aging.Readmore

New Study Finds Where You Live Affects Recovery After a Hip Fracture

Older adults in economically disadvantaged neighborhoods spend nearly a month less at home after a hip fractureReadmore

New Study Shows Alzheimer’s Disease Can Be Reversed in Animal Models to Achieve Full Neurological Recovery, Not Just Prevented or Slowed

A new study shows that restoring brain energy balance by maintaining NAD+ levels can reverse Alzheimer’s-like brain damage and cognitive decline in advanced disease models, challenging the long-held belief that Alzheimer’s is irreversible.Readmore

Clearing the brain of aging cells could aid epilepsy and reduce seizures

Researchers found that temporal lobe epilepsy may be driven by prematurely aging brain cells, and eliminating these senescent cells in mice reduced seizures, improved memory, and even prevented epilepsy in some cases.Readmore

Decoding our memories: U of T researcher explores brain chemistry with new Connaught mid-career funding

U of T’s Katherine Duncan studies why memories differ and how this may predict aging or dementia.Readmore

Exploring the Connection Between Gene Expression and Aging

Scientists revealed how transcription elongation factors control cellular senescence and aging, opening new anti-aging targets.Readmore

New study offers breakthrough in detecting risk for psychosis and bipolar disorders

A study published recently in The Lancet Psychiatry has unveiled a new approach to identifying individuals at risk of developing psychotic disorders or bipolar disorder.Readmore

Digital tools can improve dementia care for people with dementia aging in place and their caregivers

This study explores whether digital communication can truly replicate the social and caregiving benefits of in-person interactions for people living with dementia and their caregivers.Readmore

New study identifies key protein driving inflammation with age

University of Minnesota researchers found that aging macrophages stay chronically inflammatory via GDF3–SMAD2/3 signaling, worsening sepsis, and that blocking this pathway reduces harmful inflammation and improves survival in preclinical models.Readmore

Three rising stars in ageing research

Neuroscientist Thomas Karikari is developing a blood test to detect Alzheimer’s-related tau proteins early, offering a less invasive and more accessible diagnostic option.Readmore

Green Mediterranean Diet Slows Brain Aging

A new study shows the green-MED diet can slow brain aging by lowering proteins linked to Alzheimer’s. Researchers highlight its potential for future blood-based brain health tests.Readmore

Women with Down syndrome may develop Alzheimer's disease more rapidly than men

UC Irvine study finds sex differences may impact treatment approachesReadmore

Broad COVID-19 vaccination makes economic sense, especially for older adults, study finds

Vaccinating every person over 65 would actually save the U.S. money, while vaccinating all younger adults would be a reasonable investmentReadmore

This Protein Slows the Aging Brain, and We Know How to Counter It

Blocking the FTL1 protein reverses age-related memory and brain decline in mice.Readmore

Restricted Blood Flow Speeds Tumor Growth by Aging the Immune System

Restricted blood flow (ischemia) accelerates cancer growth by prematurely aging bone marrow and weakening immune defenses.Readmore

Omega-3's could protect women against Alzheimer's

Omega fatty acids could protect against Alzheimer’s disease in women, new research has found.Readmore

How aging drives neurodegenerative diseases

A University of Cologne research team has identified a direct molecular link between aging and neurodegeneration by investigating how age-related changes in cell signalling contribute to toxic protein aggregationReadmore

Chronic benzodiazepine consumption impacts sleep quality in older adults, new research shows

A common insomnia treatment makes sleep quality worse than no treatment at allReadmore

Immune ageing found in the earliest stages of rheumatoid arthritis gives hope for early intervention

Researchers from University of Birmingham discover that immune ageing may be a driver of rheumatoid arthritis rather than a consequence of the diseaseReadmore

Researchers identify ways to improve communication during palliative care discharge

The study highlights key recommendations professionals can utilise to improve communication experiences during discharge into community settings.Readmore

Using new blood biomarkers, USC researchers find Alzheimer’s disease trial eligibility differs among various populations

Individuals from certain underrepresented groups were less likely to have elevated amyloid in the brain based on blood levels of p-tau217, reinforcing earlier findings.Readmore

D-CARE study finds caregiver satisfaction higher with dementia care programs than usual care

The largest U.S. dementia care clinical trial shows caregiver satisfaction is higher with both health system and community-based dementia care programs compared to usual careReadmore

Exposure to air pollution worsens Alzheimer’s disease, Penn research finds

Living in areas with high concentration of air pollution is associated with increased buildup of amyloid and tau proteins in the brains of Alzheimer’s patients, accelerating cognitive decline.Readmore

Elderly at Risk of Depression? IPB University Psychiatrist Emphasizes Family Support and Sensitivity

Depression in the elderly, often triggered by loss or illness, affects mood, energy, and quality of life. Strong family support is key to prevention and recovery.Readmore

Why Do We Lose Cognitive Ability as We Age?

Even healthy aging comes with a high risk of mental decline, and UNH researchers are investigating why at the molecular levelReadmore

Research challenges negative stereotypes about growing older

Aging today is not just decline but active living and decision-making. Research urges us to move beyond stereotypes and embrace a fresh view of older adults.Readmore

Resistance training may improve nerve health, slow aging process

Simple resistance training can help older adults slow nerve deterioration, boosting strength, independence, and fall prevention.Readmore

Korea University Study Identifies Age 70 as Cutoff for Chemotherapy Benefit in Colorectal Cancer

Largest national analysis finds oxaliplatin helps only younger stage III patients, sparing many older adults from harmful side effects.Readmore

Dormant no more: Brain protein's hidden role may reshape psychiatric and neurological treatments

Johns Hopkins scientists uncover how GluD brain proteins could be targeted to treat psychiatric and neurological disorders.Readmore

Cocoa extract supplement reduces key marker of inflammation and aging, study finds

COSMOS researchers found cocoa extract lowered inflammation marker hsCRP, linking it to heart-protective and healthy aging benefits.Readmore

Age 70 identified as cutoff for chemotherapy benefit in colorectal cancer

Colorectal cancer deaths are rising in older adults, raising debate on oxaliplatin’s use despite its toxic side effects.Readmore

Why women bear the burden of dementia: Unraveling the sex gap

Nearly two-thirds of Americans diagnosed with Alzheimer's disease are women, and they often experience faster cognitive decline than men. The reasons behind this sex gap have largely remained a mystery until now.Readmore

Increasing levels of the protein PI31 demonstrates neuroprotective effects in mice

Boosting PI31 restores proteasome transport, prevents synaptic protein buildup, and protects against neurodegeneration in flies and mice.Readmore

Preserving synaptic communication may be key to preventing neurodegeneration

Boosting PI31 enhances proteasome activity at synapses, reversing key neurodegeneration hallmarks in animal models.Readmore

Older adults can bounce back from health and emotional challenges

A Canadian study shows nearly 1 in 4 older adults aged 60+ can regain optimal well-being within three years, proving it’s never too late to bounce back.Readmore

Ole Miss Research on Aging Earns Gold Honor

University of Mississippi research finds livestreamed nature videos may reduce isolation and boost alertness in older adults.Readmore

Healthy habits can make your brain age more slowly, study finds

Healthy habits like sleep, support, and no tobacco may slow brain aging by up to 8 years.Readmore

NIH funds first-of-its-kind center to study resilience and aging

The Center for SUNSHINE is a national hub advancing research, innovation, and community-driven solutions to strengthen resilience and healthy aging.Readmore

New research uncovers how caffeine could slow cellular ageing

A new study suggests caffeine may help slow cellular aging.Readmore

New clues as to why drugs are effective for Alzheimer’s disease

A team of scientists including UCL researchers has tested four anti-amyloid Alzheimer’s therapeutics to find out how the drugs bind to toxic amyloid beta protein to tackle the disease.Readmore

Researchers discover a novel gene variant in Finns that increases the risk of Alzheimer’s disease

A rare TYROBP gene variant found in Finns significantly raises Alzheimer's risk by impairing microglial function, highlighting the role of inflammation and protein stress in early disease stages.Readmore

Scientists discover potential new targets for Alzheimer’s drugs

Pathways involved in DNA repair and other cellular functions could contribute to the development of Alzheimer’s.Readmore

New Pace of Aging Measurement Reveals Trajectories of Healthspan and Lifespan in Older People

Faster Pace of Aging Linked to Greater Risk of Chronic Disease, Cognitive Decline, Disability, and Early DeathReadmore

How AI can improve dementia detection 19 May 2025

Researchers at NCHA, a Monash University–Peninsula Health collaboration, have enhanced hospital dementia detection by combining traditional screening with AI.Readmore

Use of Metformin Associated with Exceptional Longevity Among Older Women

Interest is growing in gerotherapeutics like metformin, a diabetes drug under study for its potential to slow aging by targeting key aging-related processesReadmore

UQ study finds dementia risk drops across generations

A person aged 75 to 80 is less likely to have dementia today compared to someone of the same age several decades ago, a University of Queensland study has found.Readmore

Study uncovers RNA changes in Alzheimer’s disease

Researchers at McGovern Medical School have uncovered cellular changes in the brain during Alzheimer’s, offering new insights that could aid future treatments. Readmore

Shorter Telomeres Linked to Increased Risk of Age-Related Brain Diseases

Mass General Brigham scientists found that healthy lifestyle choices may reduce the risk of age-related brain diseases linked to shorter telomere length.Readmore

Vanderbilt biologist receives $1.3M Keck grant to study what birds’ longevity could mean for human agingVanderbilt biologist receives $1.3M Keck grant to study what birds’ longevity could mean for human aging

Pet parrots often outlive humans, and researchers are studying them to uncover secrets of longevity that could benefit people.Readmore

Brain biomarkers of Alzheimer's disease can be detected as early as middle age 14.07.2025 Press release News

Alzheimer’s may begin in middle age, and blood biomarkers could enable earlier, targeted prevention. Readmore

Demystifying the Link Between Major Depression and Alzheimer’s Disease

Depression may contribute to up to 1 million U.S. dementia cases, highlighting a treatable risk factor for Alzheimer’s.Readmore

SARS-CoV-2 Causes Buildup of Alzheimer’s-Related Peptides in the Retina

A Yale study links post-COVID brain fog to a potential treatment target and sheds light on Alzheimer’s origins.Readmore

Move more, think sharper: How physical activity boosts brain health in ageing

Even just five minutes of moderate-to-vigorous exercise daily can significantly boost brain health in older adults, improving memory and cognitive function.Readmore

Dementia protection linked to where the body lies – belly fat a risk factor

Men with high belly fat face a higher risk of dementia, according to a Monash University study of over 17,000 older adults in the ASPREE Study.Readmore

The maths behind early morning awakenings, the effects of evening light and the naps of babies

Mathematical modeling of sleep explains why babies nap inconsistently and older adults wake earlier, a University of Surrey study finds.Readmore

Your skin buckles as you age – and that’s why wrinkles form

Wrinkles form as aging skin buckles from stretching in one direction and contracting in another, Binghamton-led research shows. Readmore

Nature-Inspired Virtual Reality Boosts Emotional Well-Being In Older Adults Living With Dementia

Texas A&M study finds immersive VR nature experiences improve mood and quality of life.Readmore

Antiviral Treatment Fails to Slow Early-Stage Alzheimer’s

Trial shows herpes drug valacyclovir fails to slow early Alzheimer’s, despite earlier HSV-Alzheimer’s link.Readmore

FSU Study Highlights Importance of Psychological Resilience in Aging and Widowhood

FSU study links psychological resilience to better widowhood recovery, especially in older women.Readmore

Dementia’s broad reach: More than 1 in 4 families of older adults at risk for providing care

Over a quarter of U.S. families include an older adult with dementia, highlighting widespread caregiving challenges and the urgent need for support systems.Readmore

Internalizing Stress May Lead to Cognitive Decline in Older Chinese Americans

A Rutgers Health research study shows the impact of psychological strain on brain healthReadmore

Preventing falls in older adults with mild cognitive impairment

A team led by researchers in the School of Nursing has developed a multicomponent intervention that uses passive monitoring and behavioral support to help reduce falls in at-risk older adults.Readmore

Brown University neuroscientists help identify a biomarker for Alzheimer’s disease progression

Researchers at the Carney Institute for Brain Science have identified electrical activity in the brain that could predict progression to Alzheimer’s disease.Readmore

Exposure to nanoplastics could induce spread of Alzheimer’s disease from the brain to other other organs

Nanoplastics may accelerate Alzheimer's and spread damage from brain to liver, heart, and gut.Readmore

‘Virtual’ Socializing Greatly Eases Isolation in Seniors with Dementia

Researchers analyzed 1,900 virtual group events and found the strongest predictor of social engagement was the number of people actively speaking. Readmore

Memory is impaired in aged rats after 3 days of high-fat eating

Study finds diet-related brain inflammation without metabolic changesReadmore

Alzheimer’s disease, dementias chronically undiagnosed yet early detection rarely used

A University of Michigan study finds cognitive screening for Alzheimer’s remains underused despite its benefits. Researchers emphasize the need for greater awareness and access to early diagnosis and treatment.Readmore

AI may aid in the timely diagnosis of schizophrenia and bipolar disorder

Schizophrenia and bipolar disorder are severe mental illnesses that emerge in early adulthood, requiring precise diagnosis for effective treatment, though diagnosis can be complex.Readmore

Mount Sinai-Led Research Team Identifies Underlying Mechanisms of Age-Related Dysfunction in Glands Crucial to Eye Function

Mount Sinai researchers identified stem cell mechanisms behind age-related meibomian gland degeneration, paving the way for new treatments for evaporative dry eye disease.Readmore

Herpesviruses may contribute to Alzheimer’s disease via transposable elements

HSV-1 is associated with Alzheimer’s-associated transposable elements in infected, Alzheimer’s-affected brains, which may be reversed through available drugs.Readmore

Immune cells may lead to more Parkinson’s cases in men

LJI scientists uncover autoimmune response that may help explain why Parkinson's disease is twice as common in male patientsReadmore

Rice researchers unravel menopause timing, shedding light on ovarian aging and fertility

A new study from Rice University uses stochastic analysis to model ovarian aging, predicting menopause timing with greater accuracy. The findings reveal how follicular transitions influence variability and population-wide trends in menopause.Readmore

New AI Model Measures How Fast the Brain Ages

The first-of-its-kind tool can non-invasively track the pace of brain changes using MRI scans; faster brain aging closely correlates with a higher risk of cognitive impairment.Readmore

Study: Extreme Heat May Speed Up Aging in Older Adults

People in neighborhoods that experience more days of high heat show faster aging at the molecular level than residents of cooler regions, say USC researchers.Readmore

Digital Program Reduces Fall Risk and Boosts Strength in Older Adults

Study highlights the success of an online exercise program tailored for seniorsReadmore

Loyal Receives FDA Acceptance of Reasonable Expectation of Effectiveness for Senior Dog Lifespan Extension

Loyal, a clinical-stage animal health company, has secured FDA acceptance for LOY-002’s effectiveness in extending senior dogs' lifespan and raised $22M in funding to advance its longevity drug portfolio.Readmore

Key protein identified for understanding and treating Alzheimer’s disease

Researchers at the University of Cologne have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represents a new target for future treatmentsReadmore

Shared Pathways in HIV and Aging May Contribute to Heart Failure Risk

Scientists have identified a unique protein signature in the blood of people living with HIV, linked to aging and increased heart failure risk. This discovery may help refine risk prediction models and uncover new therapeutic targets for heart failure.Readmore

Among Older Women, Hormone Therapy Linked to Tau Accumulation, a Hallmark of Alzheimer’s Disease

Menopausal hormone therapy (HT) linked to faster tau accumulation in women over 70, potentially increasing Alzheimer’s risk. Timing of HT initiation is crucial.Readmore

The ‘Silent’ X Chromosome Gives the Aging Female Brain a Boost

In a surprise, work in mice has found that the dormant X chromosome in females can reawaken late in life and turn on genes that keep the brain healthy.Readmore

Scientists Identify Critical “Midlife Window” for Preventing Age-Related Brain Decline

Groundbreaking research reveals metabolic interventions could help prevent cognitive agingReadmore

Brain mapping unlocks key Alzheimer’s insights

A UTA, University of California–San Francisco study explores why some nerve cells are more vulnerable to neurodegenerationReadmore

Healthy Aging Policy Innovation Lab releases first provincial study on Meals on Wheels program

UNB’s Healthy Aging Policy Innovation Lab finds Meals on Wheels boosts seniors’ independence, nutrition, and social connection in New Brunswick.Readmore

Blood-platelet screening in midlife could identify early risk for Alzheimer’s disease

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer’s disease decades ahead of time, allowing for possible preventive therapy.Readmore

Anti-Amyloid Therapy Does Not Change Short-Term Waste Clearance in Alzheimer’s

After lecanemab treatment, MRI scans show no short-term change in waste clearance function in Alzheimer’s patientsReadmore

UK researchers use gene ‘switch’ to reverse Alzheimer’s risk

A new UK gene-switch model shows converting APOE4 to APOE2 can reduce Alzheimer’s changes in mice.Readmore

Uncovering the hidden cellular connections that bridge aging and disease

Using machine learning, Yale researchers have developed a new imaging technique that can unlock signs of aging and disease in human cells.Readmore

Eating alone linked to poorer nutrition in older adults

Older adults who regularly eat meals alone are more likely to experience poorer nutrition and health outcomes than those who share meals with others, new research by Flinders University has found.Readmore

Targeting brain immune cells could restore Alzheimer’s-related lipid imbalance, UT Health San Antonio research shows

Early findings showed abnormal brain lipids in Alzheimer’s, but research has long focused mainly on amyloid and tau.Readmore

Mount Sinai Scientists Reverse Aging in Blood Stem Cells by Targeting Lysosomal Dysfunction

Study published in Cell Stem Cell reveals a technique that renews aged blood-forming stem cells and may help prevent age-related blood disordersReadmore

Inspired by a Family’s Struggle, a Scientist Helps Uncover Defense Against Alzheimer’s Disease

A personal story from China helped drive Rutgers research that reveals how a rare genetic mutation protects the brainReadmore

Inhibiting a master regulator of aging regenerates joint cartilage in mice

Osteoarthritis due to aging or injury affects 20% of the U.S. population. A Stanford Medicine led study found that blocking a ‘gerozyme’ reverses cartilage loss in mice and human tissue.Readmore

Social support predicts longevity and improved quality of life among older adults

Recent University of Eastern Finland studies reveal that strong social support significantly boosts longevity and quality of life in older adults.Readmore

New AI technology can provide rapid and reliable dementia diagnosis

“New AI models from Örebro University use EEG signals to detect dementia early with high accuracy.”Readmore

Texas A&M scientists use ‘nanoflowers’ to recharge aging and damaged cells

Breakthrough method boosts stem cells’ ability to share mitochondria, offering hope for treating aging, heart disease and neurodegenerative disorders by restoring cellular energy.Readmore

Poorer heart health in middle age linked to increased dementia risk

People with signs of damage to their heart during middle age are more likely to develop dementia in later life, according to a new study led by UCL researchers.Readmore

It May Take a Village: Purdue Research Links Neighborhoods to Slower Cognitive Decline

Living in culturally and socially enriched neighborhoods can help older adults maintain stronger cognitive health as they age.Readmore

Aging Brain Retains a Remarkable Capacity for Resiliency

New study shows that in middle-age, the brain can still respond to treatment that helps it to repair, function more effectively Readmore

It’s not just chronic pain; it’s how many places it hurts that may affect the brain

UB researchers report that the number of pain sites, rather than pain itself, is a key predictor of cognitive decline with age.Readmore

Kidney health affects Alzheimer’s blood biomarkers but not dementia risk

A new study shows kidney health affects Alzheimer’s biomarkers in blood but doesn’t raise overall dementia risk.Readmore

Creating a brain booster for older people

A new plant-based nutrient that could boost older people’s brain health is being brewed in the lab of University of Auckland Professor Siew-Young Quek.Readmore

Can lost vision be restored?

Leveraging neuroscience, optics, and healthcare, URochester researchers are at the forefront of understanding vision loss and restoring eyesight.Readmore

Predicting Alzheimer’s earlier

UD’s DementiaBank outshines global competitors, driving machine-learning advances in early dementia predictionReadmore

Aging midbrain neurons face energy crisis linked to Parkinson’s

Aging makes midbrain dopamine neurons vulnerable to fuel shortages, linking to Parkinson’s.Readmore

Older age, kidney disease, stroke tied to higher risk for potentially deadly illness after West Nile infection

Older adults with CKD, cerebrovascular disease, or immune issues face higher risk of severe West Nile neuroinvasive disease.Readmore

Computing new enzymes to fight neurodegenerative disease

Kejun Ying combines computational biology and protein design to develop novel therapies targeting neurodegenerative diseases and aging.Readmore

Artificial Intelligence Detects Early Signs of Aging from Chest X-Rays

New study finds deep learning model predicts heart, lung, and frailty changes more accurately than DNA-based aging clocks.Readmore

How artificial intelligence is shaping our understanding of age(ing)

A study from Karl Landsteiner University reveals that the relationship between AI and ageing is complex and socio-technical, shaped by power, participation, and everyday practices rather than just technology.Readmore

Pilot study: Branched-chain amino acids may help physical, mental fatigue in older adults

A UT Health San Antonio study showed that adding BCAA supplements to exercise helped older adults reduce fatigue and depression while slightly boosting strength.Readmore

Circadian clock protein linked to brain aging and neurodegenerative disease

Impeding a link between the body's natural clock and the brain may help reduce neurodegeneration in mice modeling Alzheimer's disease, according to a new study led by researchers at WashU Medicine and published in Nature Aging.Readmore

Older adults with prediabetes, low levels of education at highest risk for cardiovascular complications

UB study links low education and economic instability to higher cardiovascular risks in older adults with prediabetes.Readmore

Study: ‘Man’s Best Friend’ Slows Cellular Aging in Female Veterans

Training service dogs may help slow cellular aging and reduce stress in female veterans with PTSD.Readmore

Ohio State study shows potential treatment for age-related heart diseases

Researchers at Ohio State University developed a non-viral gene therapy using tissue nanotransfection to boost brown fat–derived lipokine 12,13-diHOME, reversing age-related heart decline.Readmore

UK researchers uncover key brain cell communication breakdown in Alzheimer’s disease

UK researchers found that faulty signaling between brain cells and blood vessels disrupts energy flow in Alzheimer’s.Readmore

Common hospice medications linked to higher risk of death in people with dementia

New study of those prescribed benzodiazepines or antipsychotics after hospice enrollment highlights two hospice policy issues Readmore

Longevity gene from supercentenarians offers hope for disease that causes rapid ageing in children

Scientists have discovered that “longevity genes” from centenarians may reverse heart and vessel damage in children with a rare premature aging disease.Readmore

Lending a hand to close friends boosts daily mood in older adults

Helping friends with practical tasks boosts older adults’ mood, though emotional support may lower men’s positivity, highlighting gendered differences in social well-being.Readmore

UIC study of blood stem cells asks: Can we slow aging on a cellular level?

UIC researchers found that restoring platelet factor 4 can rejuvenate aging blood stem cells and reverse immune decline.Readmore

UAB awarded grant to launch space-based study on aging

UAB researchers received a $2.8M NIH grant to study Alzheimer’s by sending human brain organoids to space to explore accelerated aging and disease mechanisms.Readmore

Ways to Slow Down Aging

Stanford research suggests two key aging shifts around ages 44 and 60, though experts urge caution in interpreting the findings.Readmore

Molecular fingerprint predicts physical fitness in older adults

A new study shows that a simple blood test, highlighting aspartate as a key biomarker, can reveal how physical activity shapes healthier aging and may protect against dementia.Readmore

Dementia linked to problems with brain’s waste clearance system

Problems with the brain’s waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the risk of dementia.Readmore

Uncovering Hyper-Maturity and Accelerated Aging in the Hippocampus: Stress, Serotonergic Disruption, and Psychiatric Vulnerability as Underlying Factors

Researchers at Fujita Health University discovered that excessive hippocampal aging, or "hyper-maturity," is linked to anxiety and may offer new insights into psychiatric and aging research.Readmore

Research into wild chimpazees’ changing tool use suggests evolutionary origins of Alzheimer’s disease and related disorders.

For decades, scientists assumed only humans experienced dementia. Now, new field observations suggest that wild chimpanzees our closest primate relatives may also show signs of cognitive decline with age.Readmore

GLIS Model as a Predictor of Outcomes in Older Adults with Heart Failure

Researchers find new GLIS model outperforms existing tests in identifying frailty and mortality risk in older adults with heart failureReadmore

UT Health San Antonio study finds amino acid supplement may boost exercise benefits for older adults

BCAA supplements combined with exercise may reduce fatigue, boost strength, and improve mood in older adultsReadmore

Rapid Blood Pressure Fluctuations Linked to Early Signs of Brain Degeneration in Older Adults

Moment-to-moment blood pressure fluctuations, even with normal averages, may accelerate brain shrinkage and nerve cell damage in older adults, increasing dementia risk.Readmore

A new tool for understanding chromosome abnormalities in the eggs of older women

Yale researchers have created a new method for simulating “aging-like” chromosome errors in mouse eggs to better understand female reproductive lifespan.Readmore

Even Modest Amounts of Physical Activity May Slow Alzheimer’s Disease Among At-Risk Older Adults

Walking 3,000–7,500 steps a day may slow Alzheimer’s progression and support long-term brain health.Readmore

Study Pinpoints Source of Free Radicals in the Brain that May Fuel Dementia

Weill Cornell researchers discovered that blocking free radical production in astrocytes can reduce brain inflammation and protect neurons, offering a new therapeutic path for Alzheimer’s and other dementias.Readmore

USC researchers use AI to uncover genetic blueprint of the brain’s largest communication bridge

The research team created a new AI-powered tool that identifies and quantifies the part of the brain that connects the hemispheres and made it public to accelerate neuroscience research around the globe.Readmore

Study shows why living in a disadvantaged neighbourhood may increase dementia risk

Cambridge researchers have discovered why living in a disadvantaged neighbourhood may be linked to an increase in an individual’s risk of dementia.Readmore

Diagnostic uncertainty in Parkinson's disease: New study calls for improved diagnostic processes

Study finds 17.7% of Parkinson’s diagnoses revised over 10 years, highlighting challenges in accurate, long-term diagnosis.Readmore

UCalgary researchers find important clues contributing to Alzheimer's disease

How the brain interacts with the vascular system may be key to reducing disease riskReadmore

Pioneering tests could improve the assessment of dementia in ageing Africans

International researchers have introduced two improved tests that could precisely detect cognitive dysfunction in older African adults.Readmore

AI effectively predicts dementia risk in American Indian/Alaska Native elders

UC Irvine study provides framework for how machine learning models identify novel predictorsReadmore

Older adults experience similar or even less muscle damage than young adults after exercise

Older adults experience less muscle soreness after exercise, challenging the belief that aging muscles recover more slowly.Readmore

Study strengthens link between shingles vaccine and lower dementia risk

A study in Wales suggests the shingles vaccine may reduce dementia risk by 20%, offering new hope for prevention.Readmore

Mass General Brigham Researchers Reveal 17 Modifiable Risk Factors Shared by Stroke, Dementia, and Late-Life Depression

Modifying shared lifestyle risk factors can reduce the risk of stroke, dementia, and late-life depression, according to a Mass General Brigham study.Readmore

Key differences between visual- and memory-led Alzheimer’s discovered

Differences in the distribution of certain proteins and markers in the brain may explain why some people first experience vision changes instead of memory loss in Alzheimer’s disease, finds a new study by UCL researchers.Readmore

How GPS helps older drivers stay on the roads

GPS navigation helps older adults maintain driving independence by reducing spatial challenges, according to new research.Readmore

Many older adults send their doctors portal messages, but who pays?

People covered by Medicaid are just as likely as those with private insurance to face a co-pay or other charge for sending a message to their physician or other providerReadmore

Exercise as an anti-ageing intervention to avoid detrimental impact of mental fatigue

Retired adults who habitually exercised outperformed sedentary adults in physical and cognitive tests.Readmore

Five myths about gerontology dispelled by a University of Idaho professor

Gerontology goes beyond healthcare it's a dynamic, multidisciplinary field shaping how we live, age, and thrive across all stages of life.Readmore

Linking blood flow and brain health

ME researchers are using imaging methods to learn how blood flow may impact the hippocampus.Readmore

Highly accurate blood test diagnoses Alzheimer’s disease, measures extent of dementia

A new blood test for Alzheimer’s can diagnose the disease and determine its stage, aiding in personalized treatment decisions.Readmore

Students lead breakthrough study on diabetes drugs and dementia risk

Undergraduate students at University of Galway led a major study linking GLP-1 receptor agonists to reduced dementia risk in diabetes patients.Readmore

ALS drug effectively treats Alzheimer’s disease in new animal study

NU-9 acts on a common mechanism at play in both neurodegenerative diseasesReadmore

Mizzou researchers discover natural compound may slow ALS and dementia

A new study from the University of Missouri shows a compound found in certain fruits and vegetables could hold key to treating neurodegenerative diseases.Readmore

Eye health linked to dementia risk

A University of Otago study found that retinal blood vessel changes may signal early dementia risk, offering potential for future eye-scan-based screening.Readmore

More opportunities to test for Alzheimer’s using new analytical method

A new simplified blood test for Alzheimer’s shows over 90% accuracy, making early diagnosis more accessible worldwide.Readmore

Potential Alzheimer’s Disease Therapeutic Target Identified in Brain Immune Cells

Researchers identified Tim-3 as a key microglial regulator and potential Alzheimer’s therapy target, enhancing plaque clearance and reducing neuroinflammation.Readmore

New Study Explores the Need for Expanded Long-Term Care Services to Support Aging-in-Place

A recent Johns Hopkins study underscores the urgent need to strengthen long-term care services to support aging-in-place for the growing U.S. elderly population.Readmore

Social isolation linked to poor diet in older women

A UBC study finds persistently isolated older Canadian women have poorer diet quality due to reduced fruit and vegetable intake, highlighting the impact of long-term social connection on healthy eating.Readmore

Alternative to hip replacement keeps aging athletes in the game

Birmingham hip resurfacing enables active adults to stay highly active for over a decade with fewer complications than total hip replacement, a Washington University study finds.Readmore

AI tool unlocks long-standing biomedical mystery behind Alzheimer’s, Parkinson’s

RibbonFold, a novel AI tool, accurately predicts misfolded amyloid protein structures, advancing understanding and treatment of neurodegenerative diseases like Alzheimer’s and Parkinson’s.Readmore

Alzheimer's research at SRH University: How ibuprofen affects fat metabolism in the brain

A new study reveals ibuprofen has both protective and harmful effects on brain lipid metabolism, offering insights into its complex role in Alzheimer's prevention and therapy.Readmore

Engineered microglia show promise for treating Alzheimer's, other brain diseases

UC Irvine team develops cell-based platform for brain-wide delivery of therapeutic agentsReadmore

Digital technology and AI can support workers with dementia – new research

New research highlights how digital technology can help people with dementia maintain productive working lives.Readmore

ITSN1 gene linked to risk of Parkinson’s disease

A new study identifies ITSN1 genetic variants as a major risk factor for Parkinson’s disease, paving the way for potential therapeutic advancements.Readmore

HKU study shows bad sleep harms old-age memory by disrupting the brain’s ‘waste removal system’

Poor sleep in older adults disrupts the brain’s glymphatic system, affecting memory and cognitive health.Readmore

Compound found in common herbs inspires potential anti-inflammatory drug for Alzheimer’s disease

Scripps Research scientists created a stable form of carnosic acid, observing greater memory function and other disease improvements in mice.Readmore

UMass Chan-led study finds regularly updating cognitive data improves ability to predict Alzheimer’s disease

Researchers developed a dynamic prediction model for Alzheimer's disease that continuously updates cognitive risk factors to improve early detection and intervention.Readmore

Vocal changes in birds may predict age-related disorders in people, study finds

University of Arizona neuroscientists found that aging alters gene expression in songbirds' brains, affecting vocal production—insights that may aid early diagnosis and treatment of neurodegenerative diseases like Parkinson’s and Alzheimer’s.Readmore

UWF studies positive impacts of dance for individuals with dementia

A study by a team of University of West Florida researchers, conducted with Council on Aging of West Florida’s adult day care, The Retreat, uncovered insights into the positive impact of dance on individuals living with Alzheimer’s and related dementias.Readmore

Earlier menopause and poor synaptic health could raise Alzheimer's risk: Study

These findings highlight the importance of both hormonal factors and synaptic health in influencing [Alzheimer’s disease] risk in womenReadmore

Anti-amyloid drug shows signs of preventing Alzheimer’s dementia

Clinical trial of people destined to develop early-onset Alzheimer’s disease shows eliminating amyloid from brain may prevent symptoms, supports need for confirmatory studiesReadmore

Dementia patients and their carers to be asked about direction of drug research

Cambridge researchers seek input from dementia patients and families on repurposing existing drugs for clinical trials to slow or halt disease progression.Readmore

More young people are caring for a loved one with dementia. It takes a unique toll

Caring for a loved one with dementia, particularly if they’re a parent, takes a unique emotional toll on a young person. They need better support.Readmore

Elderly neurological patients are open to in-home remote monitoring

Elderly neurological patients are open to home-based remote monitoring, with caregiver support enhancing acceptance.Readmore

Weather emergencies affect older adults' health views

People over 50 who recently experienced an extreme weather event far more likely to express concern about the effects of climate change on their healthReadmore

Understanding older care leavers’ perceptions and experiences of aged care services

A new review led by the National Centre for Healthy Ageing and Monash University highlights the challenges faced by older care leavers in aged care, emphasizing the need for trauma-informed, person-centered support.Readmore

Mass General Brigham Researchers Develop and Study an At-Home Smell Test for Early Detection of Alzheimer’s Disease

A new study suggests that olfactory testing may help detect early cognitive impairment, potentially aiding in the early diagnosis of neurodegenerative diseases like Alzheimer's.Readmore

Healthy eating in midlife linked to overall healthy aging

Readmore

Is Increased Sleepiness in Our 80s Tied to Higher Dementia Risk?

Changing sleep patterns in older adults, especially increasing sleepiness, may double the risk of dementia, according to a Neurology study.Readmore

Pennington Biomedical Researchers Identify Neurons in Brain that Regulate Energy Levels and Body Temperature

Research shows that the brain area that helps control body temperature, energy use and eating habits uses specific chemical and neuronic pathways to influence regulating adjustments. Readmore

How Your Brain Manages Cholesterol Could Increase Alzheimer’s Risk

In breakthrough, UCSF study shows that cholesterol-hungry parts of the brain are more vulnerable to Alzheimer’s amyloid-beta plaques, suggesting potential treatment targets.Readmore

AI-driven robotics research aims to enhance care for older adults with Alzheimer’s

AI-powered robot Ruyi is being studied at Case Western Reserve University to enhance senior care and support individuals with early-stage Alzheimer's.Readmore

Throat microbiome holds clues to older Australians’ health

Flinders University researchers have identified Staphylococcus aureus as a potential microbial marker for assessing health risks in aged care residents.Readmore

New Frailty Measurement Tool Could Help Identify Vulnerable Older Adults in Epic

Mass General Brigham researchers developed an AI-driven tool that identifies frailty in older adults using electronic health records, helping predict emergency care needs, rehospitalization, and mortality risk.Readmore

His genes forecast Alzheimer's. His brain had other plans.

Doug Whitney, 75, carries a rare Alzheimer’s-causing gene mutation but remains symptom-free, possibly due to high levels of heat shock proteins. Scientists are studying his case to uncover new protective strategies against the disease.Readmore

1 in 5 older adults get infections after heart surgery, and women have a 60% higher risk

Investigators say postoperative infections may be greatly underestimatedReadmore

Understanding How Metabolism Contributes to Parkinson’s Disease

Northwestern Medicine researchers discovered that mitochondrial dysfunction in Parkinson’s disease disrupts metabolism, leading to neuronal damage. Targeting alpha-ketoglutarate dehydrogenase may offer new therapeutic possibilities.Readmore

One-third of older Canadians at nutritional risk, study finds

A University of Waterloo study found that one-third of Canadian adults aged 55+ are nutritionally at risk, increasing healthcare use, highlighting the need for routine nutrition screening like SCREEN-8.Readmore

Prenuvo Announces it Had Raised $120M to Advance Preventative Health, Launches Novel FDA-Cleared AI-Powered Products

Prenuvo, a leader in proactive whole-body MRI screening, raised $120M in Series B funding and secured FDA clearance for its AI-powered body composition report, reinforcing its role in preventative healthcare innovation.Readmore

‘Healthy’ Vitamin B12 Levels Not Enough to Ward Off Neuro Decline

UCSF-led study calls for new recommendations and supplements for older adults that may offer better brain protection.Readmore

Older people in England report greater life satisfaction than before the Covid pandemic

Older people have greater life satisfaction and sense of life’s worth than they did before the Covid-19 pandemic, finds a new study led by a UCL researcher.Readmore

Neko Health raises $260m Series B

Preventative healthcare tech company Neko Health, co-founded by Hjalmar Nilsonne and Daniel Ek, has secured $260M in Series B funding.Readmore

Vertex Announces FDA Approval of JOURNAVX™ (suzetrigine), a First-in-Class Treatment for Adults With Moderate-to-Severe Acute Pain

Vertex Pharmaceuticals has received FDA approval for JOURNAVX™ (suzetrigine), a first-in-class treatment for moderate-to-severe acute pain in adults. This marks a major advancement in non-opioid pain management, offering a new option for patients in need.Readmore

Innovative theatre project bringing laughter to people living with dementia

A pioneering new theatre project, created with help from Swansea University, has been bringing joy, laughter, and meaningful social connection to care homes in South Wales.Readmore

ALS survival may be cut short by living in disadvantaged communities

Social determinants of health negatively impact many diseases, including neurological conditionsReadmore

New study looks at nostalgia, comfort in food preparation for older adults

New Washington State University research highlights the importance of nostalgia, comfort, and texture variety in prepared meals for older adults, enhancing both enjoyment and nutrition.Readmore

Luteolin, an antioxidant in vegetables, may contribute to the prevention of hair graying

Luteolin, an antioxidant in vegetables, may help suppress graying hair, according to Nagoya University research.Readmore

Blood test shows promise for early detection of dementia

Research findings focus on people with a sleep disorder, but could have broader implicationsReadmore

Treatment for Alzheimer’s may lie in the brain’s own cleanup crew

Brain’s immune cells cleared plaques, restored a healthier brain environment in immunized patient brainsReadmore

A New Approach to Alzheimer’s? Study Finds Promising Therapeutic Target

New technique reveals how axon swellings could be treated in Alzheimer’s.Readmore

How the brain switches between persevering, trying something new, or giving up

A UCL-led study in mice has identified brain circuits responsible for decision-making, regulating perseverance, exploration, and disengagement. These findings provide insights into cognitive flexibility and adaptive behavior.Readmore

New study uncovers how genes influence retinal aging and brain health

JAX researchers used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseasesReadmore

Life span increases in mice when specific brain cells are activated

Brain cells communicate with fat tissue to produce cellular fuel, counteract effects of agingReadmore

Telomir Pharmaceuticals Confirms Lifespan Restoration and Normalization of Accelerated Aging in Preclinical Model of Progeria A Rare Genetic Disorder Causing Rapid Aging

The research, utilizing C.elegans models, demonstrated that Telomir was able to reverse shortened lifespans and restore normal aging processesReadmore

Meet the newly discovered brain cell that allows you to remember objects

Scientists at UBC’s faculty of medicine have discovered a new type of brain cell that plays a central role in our ability to remember and recognize objects.Readmore

Next-gen Alzheimer’s drugs extend independent living by months

New analysis recasts benefits of treatment in relation to day-to-day impacts on patients’ livesReadmore

Is Plant Protein a Key to Healthy Aging for Women?

A recent major study of women showed that protein—particularly protein from plant food—is a key ingredient in healthy aging in women. More than 45,000 women participated in the study, and the results back up earlier research that emphasizes the benefiReadmore

Could a Drug Prevent Hearing Loss from Loud Music and Aging?

Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss.Readmore

Worm study shows hyperactivated neurons cause aging-related behavioral decline

Researchers at Nagoya University found that age-related cognitive decline is caused by neuronal hyperactivation, not reduced activity. Dietary changes may help regulate this and support healthy brain aging!Readmore

Schizophrenia and Aging May Share a Biological Basis

Synchronized changes in gene activity in brain cells may underlie cognitive impairment in both conditionsReadmore

Opening for a new type of drug for Alzheimer’s Disease

In Alzheimer’s disease, the tau protein changes in harmful ways. First, it clumps into small, soluble groups that are released from nerve cells and may spread damage to other cells.Readmore

Diagnosing Alzheimer’s disease using blood tests: p-tau biomarkers not as disease-specific as previously thought

Blood p-tau, once thought AD-specific, is also elevated in ALS, challenging its diagnostic precision but offering potential for ALS monitoring.Readmore

Do heatwaves make us age faster?

Researchers fear that climate change could contribute to increased rates of biological ageing, with implications for people’s long-term health. Readmore

Genetic research unlocks new ways to prevent and treat multiple long-term conditions

The largest study to date to analyse millions of both genetic and patient records on the long-term health conditions of later life has identified opportunities for new ways to prevent and treat multiple overlapping conditions.Readmore

Jefferson Investigates: Mood Changes after TBI, Chlamydia’s Cellular Tricks, Modulation of Pain Signals

Exploring depression and apathy in older TBI patients; how chlamydia survives in human cells; the molecular mechanisms behind intensified pain signals.Readmore

How air pollution and wildfire smoke may contribute to memory loss in Alzheimer’s disease

Scripps Research scientists discovered how a chemical modification of a key brain protein—potentially triggered by climate change-induced air pollution, pesticides, wildfires and processed meats—disrupts normal brain cell function.Readmore

Mouth bacteria may hold insight into future brain function

The bacteria in your mouth and on your tongue may be linked to changes in brain function as you age, new research suggested. Readmore

Researchers make breakthrough in bioprinting functional human heart tissue

Researchers at University of Galway have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development.Readmore

FDA Approves LEQEMBI® (lecanemab-irmb) IV Maintenance Dosing for the Treatment of Early Alzheimer's Disease

The FDA has approved a new once-every-four-weeks maintenance dose of lecanemab-irmb for early Alzheimer’s disease. This schedule may make it easier for patients and caregivers to continue treatment.Readmore

A Fasting-Refeeding Paradigm Rejuvenates Old Stem Cells

The new study indicates that there is a way to turn back the clock to a younger time and rejuvenate these blood stem cells, restoring their ability to regenerate and fight off age-related diseases.Readmore

Important Grant to Study Health Equity in Alzheimer’s Treatment

NIH support will allow Brian Callaghan, M.D., to study the medical and cost effectiveness of new Alzheimer’s medications in underrepresented communities.Readmore

Olive oil may reduce risk of death from dementia

People who incorporate olive oil into their everyday diet may decrease their risk of dementia-related death, according to a new study by Harvard T.H. Chan School of Public Health.Readmore

Multi-year CIHR grant supports McMaster study at the intersection of aging and infectious disease

McMaster University researchers have received $750,000 from the Canadian Institutes of Health Research (CIHR) for a multi-year study into the connection between respiratory infections and brain aging.Readmore